Was there today & had brunch.
All I can recommend is to use BART as much as possible to get around.
It doesn't cover every area but it's relatively fast & cheap.
Bring some good walking shoes.
You probably will be walking a lot.
I'd recommend against renting a car.
Its easy to get lost, hard to find parking, & difficult to fight the urge plowing into bicyclists.
Yelp.com will be useful in terms of looking for restaurants, bars/clubs, and local interests.
They have an app for iphone & android phones.
Berkely isn't bad either.
I would probably avoid venturing out to the East/South bay as there really isn't a lot going there.
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